The AI of Everything: Why Hardware Startups are the New Software Winners

As a Deal Lead at Keiretsu Forum SoCal, I spend my days sifting through pitches, and the investment narrative has shifted dramatically. While the previous decade was dominated by purely software and platform models, the next wave of Artificial Intelligence (AI) is being built on new, proprietary hardware. This is why smart hardware startups are becoming the most compelling investment opportunities in the Consumer Electronics space and beyond.

CES is ground zero for this shift. It’s no longer just about incremental upgrades; it’s about specialized sensors, edge processing chips, and unique form factors designed to bring AI off the cloud and into the human experience.

The Software Trap and the Hardware Moat: 
Building Data Defenses Many founders think AI is the solution, but without proprietary data collected by novel hardware, AI is a commodity. For investors, the hardware creates the "moat", a barrier to entry that pure software players cannot easily cross. 

Our K4SoCal portfolio companies perfectly illustrate this concept: 

  • Lumenuity (Optical Hardware): Their core strength lies in their unique optical designs that invented by a team including the advisor who invented the CMOS sensor and led by a former Chief Scientist from the brain-machine company Kernel. Lumenuity embodies the principle that superior hardware is the prerequisite for collecting the higher-resolution, cleaner data required to train next-generation AI algorithms, whether for consumer imaging or industrial inspection.

  • Neurava (Wearable Hardware): Their value isn't just the algorithm that identifies cardiorespiratory dysfunction associated with SUDEP (Sudden Unexpected Death in Epilepsy). It is their proprietary wearable device that can continuously and accurately collect a unique, high-fidelity physiological data set. This hardware-driven data collection solves a massive unmet need and provides a defensible foundation for their AI lead.

  • Interro IQ (Flow Cytometry AI Platform): While a software platform, its value is directly tied to the proprietary, complex data from expensive medical hardware. Interro IQ’s AI brings Interoperability and Velocity to the challenging field of Flow Cytometry. By aggregating and accelerating the interpretation of data generated by specialized flow cytometers, Interro IQ effectively acts as a "Hardware Data Accelerator," unlocking the massive value trapped within highly specialized diagnostic equipment.

My Personal Takeaway:

Bet on the Engineers For our K4SoCal members, the trump card is getting close to the entrepreneurs, especially the engineers who solve the hard, physical problems. In consumer electronics and MedTech, it’s easy to prototype, but difficult to manufacture at scale. When evaluating pitches in this space, I look for founders who not only have a compelling AI vision but also have mastered the supply chain and designed the proprietary hardware that feeds their algorithms.

The next $100B company won't just be using AI; it will be built on a proprietary piece of hardware that enables a new kind of AI. I am excited to see what innovations we discover at CES that confirm this trend.
Yukuang Wei (AK)

Blending global leadership and startup insight to fuel early-stage growth and investor engagement.

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